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Page 1: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Valve mitrale: enfants

Page 2: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Ø  complexes, atteintes très variables Ø  étiologie: congénitale (rhumatismal) Ø  malformations cardiaques associées Ø  principes

- évaluation fonctionnelle - réparation fonctionnelle ( et pas anatomique !) - pas d’anneau prothétique

Page 3: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Evaluation fonctionnelle Ø  ETT pré-op Ø  ETO pré-op immédiat +++ Ø  confrontation aux constatations

chirurgicales Ø  ETO per-op et post-op

Page 4: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

left atrial approach

Page 5: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

left atrial approach

Page 6: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

bi-atrial approach

Page 7: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

bi-atrial approach

Page 8: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Classification fonctionnelle 1/ « jeu » valvulaire normal - dilatation isolée de l�anneau +++ - fente mitrale ++ - double orifice - « defect » tissu valvulaire fuite mitrale

Page 9: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Réparation fontionnelle « jeu » valvulaire normal

Ø  dilatation isolée de l�anneau - annuloplastie (fil résorbable) - annuloplastie semi-circulaire - pas d�anneau prothétique Ø  fente mitrale: fermeture Ø  double orifice: - fermeture fente orifice principal - orifice accessoire : rien +/_ fermeture

Ø  « defect » tissu valvulaire: extension péricarde

Page 10: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

annuloplastie

Page 11: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

mitral cleft closure

Page 12: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

mitral cleft closure

Page 13: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

double orifice

Page 14: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Dilatation anneau

Fuite mitrale

Perforation

Page 15: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Classification fonctionnelle 2/ prolapsus valvulaire - absence ou rupture de cordage - cordage étiré - m. papillaire étiré fuite mitrale

Page 16: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 17: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Réparation fonctionnelle prolapsus valvulaire

Ø  absence ou rupture de cordage - résection quadrangulaire (valve postérieure) - transposition cordage (valve antérieure) - cordage artificiel en goretex Ø  cordage étiré - raccourcissement cordage - cordage artificiel en goretex Ø  m. papilaire étiré -raccourcissement m. papillaire

Page 18: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

posterior leaflet prolapse

Page 19: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

anterior leaflet prolapse :

chordal transposition

Page 20: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

anterior leaflet prolapse :

chordal transposition

Page 21: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

chordal transposition

Page 22: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

artificial PTFE chordae

Page 23: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

chordal shortening

Page 24: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

papillary muscle shortening

Page 25: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

edge-to-edge repair (Alfieri)

Page 26: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Classification fonctionnelle 3/ « jeu » valvulaire réduit

Ø  avec m. papillaires normaux - ring ou anneau supra-valvulaire Ø  avec m. papillaires anormaux - fusion m. papillaire-commissure - valve en parachute - hammock - agénésie

fuite et sténose (++) mitrale

Page 27: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 28: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Réparation fonctionnelle « jeu » valvulaire réduit Ø  avec m. papillaires normaux - ring ou anneau supra-valvulaire - excision / énucléation - malformation mitrale associée +++

Page 29: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 30: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 31: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Réparation fonctionnelle « jeu » valvulaire réduit Ø  avec m. papillaires anormaux - commissurotomie - fenestration cordage - fenestration m. papillaire

- But: retarder le RVM

Page 32: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 33: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 34: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 35: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

RVM Ø Valve mécanique - position annulaire - position supra-annulaire Ø  l�opération de Ross mitral

Page 36: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 37: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

sutures superiorly in the left atrium near the aortic valveand repositioning this portion of the prosthetic valvemore proximally in the left atrium during the sameoperation. Although this child did well hemodynami-cally, she developed recalcitrant supraventricular ar-rhythmias uncontrolled by multiple antiarrhythmics.Seven weeks postoperatively, she had placement of abiventricular pacemaker with percutaneous ablation ofher atrioventricular node, which effectively controlledher arrhythmias. Two other patients (Patients 11 and 15)had pacemaker placement postoperatively for persistentnodal rhythm or sick sinus syndrome.

There were three early episodes of thrombosis of oneof the prosthetic valve leaflets (Patients 6, 10, and 14).Two episodes were related to inadequate coagulation.Two responded to thrombolytic therapy without surgicalintervention. The third patient is now 6 years aftersupra-annular MVR and tolerates one chronically stuckprosthetic leaflet. The other 2 patients had valve fluoros-copy both before and after the thrombotic event, whichshowed normal prosthetic valve leaflet movement.

ReoperationsOn average follow-up of 4.3 ! 2.8 years, 8 of the 14survivors required reoperation, including 8 redo MVRsin 6 patients (Table 2). The interval from original supra-annular MVR to first redo supra-annular MVR rangedfrom 5 months to 10 years (mean 3.8 years). The primaryindication for redo supra-annular MVR was chronicpannus formation in four and acute thrombus in two.One patient had 3 redo supra-annular MVRs (Table 2). In3 patients, one leaflet of the prosthetic valve was noted tobe stuck due to pannus ingrowth. Four of the six childrenwho had redo supra-annular MVR were converted to abioprosthetic valve, due to difficulties with anticoagula-tion control, valve thrombosis, or bleeding difficulties. Allpatients had the new mitral valve placed in the supra-annular position—none had the new valve positioned in

Fig 1. (A)Operative technique. For patients without an atrioventricu-lar septal defect, a standard left atrial incision is performed anteriorand parallel to the right pulmonary veins. This can be extended ontothe dome of the left atrium behind the superior vena cava. (B) Thenative mitral valve is excised entirely including the chordae and tipsof the papillary muscles. Often, an additional separate right atrialincision is helpful to allow placement of right atrial-based valve su-tures. The left atrial appendage is used as a landmark; it always ison the low pressure side of the left atrium. The distance between thepledgeted sutures and the native mitral annulus is minimized both toreduce the volume of “ventricularized” left atrium and to avoid com-pression of the pulmonary veins from the prosthesis. (C) Typically,for the anterior third of the sewing ring, the sutures are placedthrough the atrial septum with the pledget on the right atrial sideavoiding the atrioventricular node. The valve is rotated with theprosthetic valve leaflets in an anti-anatomic orientation. The excur-sion of the valve leaflets is carefully checked and the valve rotatedas necessary to minimize impingement of subvalvular tissue on thevalve leaflets. (Ao " aorta; CS " coronary sinus; IVC " inferiorvena cava; LA " left atrium; LAA " left atrial appendage; MV "mitral valve; SVC " superior vena cava).

2223Ann Thorac Surg KANTER ET AL.2011;92:2221–9 SUPRA-ANNULAR MVR

PED

IAT

RIC

CA

RD

IAC

sutures superiorly in the left atrium near the aortic valveand repositioning this portion of the prosthetic valvemore proximally in the left atrium during the sameoperation. Although this child did well hemodynami-cally, she developed recalcitrant supraventricular ar-rhythmias uncontrolled by multiple antiarrhythmics.Seven weeks postoperatively, she had placement of abiventricular pacemaker with percutaneous ablation ofher atrioventricular node, which effectively controlledher arrhythmias. Two other patients (Patients 11 and 15)had pacemaker placement postoperatively for persistentnodal rhythm or sick sinus syndrome.

There were three early episodes of thrombosis of oneof the prosthetic valve leaflets (Patients 6, 10, and 14).Two episodes were related to inadequate coagulation.Two responded to thrombolytic therapy without surgicalintervention. The third patient is now 6 years aftersupra-annular MVR and tolerates one chronically stuckprosthetic leaflet. The other 2 patients had valve fluoros-copy both before and after the thrombotic event, whichshowed normal prosthetic valve leaflet movement.

ReoperationsOn average follow-up of 4.3 ! 2.8 years, 8 of the 14survivors required reoperation, including 8 redo MVRsin 6 patients (Table 2). The interval from original supra-annular MVR to first redo supra-annular MVR rangedfrom 5 months to 10 years (mean 3.8 years). The primaryindication for redo supra-annular MVR was chronicpannus formation in four and acute thrombus in two.One patient had 3 redo supra-annular MVRs (Table 2). In3 patients, one leaflet of the prosthetic valve was noted tobe stuck due to pannus ingrowth. Four of the six childrenwho had redo supra-annular MVR were converted to abioprosthetic valve, due to difficulties with anticoagula-tion control, valve thrombosis, or bleeding difficulties. Allpatients had the new mitral valve placed in the supra-annular position—none had the new valve positioned in

Fig 1. (A)Operative technique. For patients without an atrioventricu-lar septal defect, a standard left atrial incision is performed anteriorand parallel to the right pulmonary veins. This can be extended ontothe dome of the left atrium behind the superior vena cava. (B) Thenative mitral valve is excised entirely including the chordae and tipsof the papillary muscles. Often, an additional separate right atrialincision is helpful to allow placement of right atrial-based valve su-tures. The left atrial appendage is used as a landmark; it always ison the low pressure side of the left atrium. The distance between thepledgeted sutures and the native mitral annulus is minimized both toreduce the volume of “ventricularized” left atrium and to avoid com-pression of the pulmonary veins from the prosthesis. (C) Typically,for the anterior third of the sewing ring, the sutures are placedthrough the atrial septum with the pledget on the right atrial sideavoiding the atrioventricular node. The valve is rotated with theprosthetic valve leaflets in an anti-anatomic orientation. The excur-sion of the valve leaflets is carefully checked and the valve rotatedas necessary to minimize impingement of subvalvular tissue on thevalve leaflets. (Ao " aorta; CS " coronary sinus; IVC " inferiorvena cava; LA " left atrium; LAA " left atrial appendage; MV "mitral valve; SVC " superior vena cava).

2223Ann Thorac Surg KANTER ET AL.2011;92:2221–9 SUPRA-ANNULAR MVR

PED

IAT

RIC

CA

RD

IAC

Position supra-annulaire

Page 38: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

sutures superiorly in the left atrium near the aortic valveand repositioning this portion of the prosthetic valvemore proximally in the left atrium during the sameoperation. Although this child did well hemodynami-cally, she developed recalcitrant supraventricular ar-rhythmias uncontrolled by multiple antiarrhythmics.Seven weeks postoperatively, she had placement of abiventricular pacemaker with percutaneous ablation ofher atrioventricular node, which effectively controlledher arrhythmias. Two other patients (Patients 11 and 15)had pacemaker placement postoperatively for persistentnodal rhythm or sick sinus syndrome.

There were three early episodes of thrombosis of oneof the prosthetic valve leaflets (Patients 6, 10, and 14).Two episodes were related to inadequate coagulation.Two responded to thrombolytic therapy without surgicalintervention. The third patient is now 6 years aftersupra-annular MVR and tolerates one chronically stuckprosthetic leaflet. The other 2 patients had valve fluoros-copy both before and after the thrombotic event, whichshowed normal prosthetic valve leaflet movement.

ReoperationsOn average follow-up of 4.3 ! 2.8 years, 8 of the 14survivors required reoperation, including 8 redo MVRsin 6 patients (Table 2). The interval from original supra-annular MVR to first redo supra-annular MVR rangedfrom 5 months to 10 years (mean 3.8 years). The primaryindication for redo supra-annular MVR was chronicpannus formation in four and acute thrombus in two.One patient had 3 redo supra-annular MVRs (Table 2). In3 patients, one leaflet of the prosthetic valve was noted tobe stuck due to pannus ingrowth. Four of the six childrenwho had redo supra-annular MVR were converted to abioprosthetic valve, due to difficulties with anticoagula-tion control, valve thrombosis, or bleeding difficulties. Allpatients had the new mitral valve placed in the supra-annular position—none had the new valve positioned in

Fig 1. (A)Operative technique. For patients without an atrioventricu-lar septal defect, a standard left atrial incision is performed anteriorand parallel to the right pulmonary veins. This can be extended ontothe dome of the left atrium behind the superior vena cava. (B) Thenative mitral valve is excised entirely including the chordae and tipsof the papillary muscles. Often, an additional separate right atrialincision is helpful to allow placement of right atrial-based valve su-tures. The left atrial appendage is used as a landmark; it always ison the low pressure side of the left atrium. The distance between thepledgeted sutures and the native mitral annulus is minimized both toreduce the volume of “ventricularized” left atrium and to avoid com-pression of the pulmonary veins from the prosthesis. (C) Typically,for the anterior third of the sewing ring, the sutures are placedthrough the atrial septum with the pledget on the right atrial sideavoiding the atrioventricular node. The valve is rotated with theprosthetic valve leaflets in an anti-anatomic orientation. The excur-sion of the valve leaflets is carefully checked and the valve rotatedas necessary to minimize impingement of subvalvular tissue on thevalve leaflets. (Ao " aorta; CS " coronary sinus; IVC " inferiorvena cava; LA " left atrium; LAA " left atrial appendage; MV "mitral valve; SVC " superior vena cava).

2223Ann Thorac Surg KANTER ET AL.2011;92:2221–9 SUPRA-ANNULAR MVR

PED

IAT

RIC

CA

RD

IAC

Position supra-annulaire

Page 39: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Calderone et al Circulation 2001

MVR (mechanical) < 5 years

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Page 41: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

Ebstein: enfants

Page 42: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées
Page 43: Valve mitrale: enfants - Arcothova...Valve mitrale: enfants Ø complexes, atteintes très variables Ø étiologie: congénitale (rhumatismal) Ø malformations cardiaques associées

S A

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