écho-doppler thyroïdien : impact sur la prise en charge ... · pdf fileecho mode b...

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Hervé Monpeyssen AHP Écho-Doppler thyroïdien : impact sur la prise en charge des hyperthyroïdies iodo-induites SFR-IDF 05 avril 2012

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Page 1: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Herveacute Monpeyssen

AHP

Eacutecho-Doppler thyroiumldien impact sur la prise en charge des hyperthyroiumldies iodo-induites

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie

Echodoppler Pattern + agrave +++

Doppler pulseacute VS LSN agrave eacuteleveacutees

SFR-IDF 05 avril 2012

Homme 88a

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 2: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie

Echodoppler Pattern + agrave +++

Doppler pulseacute VS LSN agrave eacuteleveacutees

SFR-IDF 05 avril 2012

Homme 88a

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 3: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie

Echodoppler Pattern + agrave +++

Doppler pulseacute VS LSN agrave eacuteleveacutees

SFR-IDF 05 avril 2012

Homme 88a

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 4: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie

Echodoppler Pattern + agrave +++

Doppler pulseacute VS LSN agrave eacuteleveacutees

SFR-IDF 05 avril 2012

Homme 88a

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 5: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie

Echodoppler Pattern + agrave +++

Doppler pulseacute VS LSN agrave eacuteleveacutees

SFR-IDF 05 avril 2012

Homme 88a

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 6: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Homme 88a

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 7: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 8: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Hyper Type 1 Hyper Type2

Meacutecanismes I- laquo carburant raquo Iodo-toxique

Thyropathie GoitreTAI autonome

non

Anticorps +- non

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente

~ 0

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien)

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

Echodoppler Pattern + agrave +++ avasculaire

Doppler pulseacute VS LSN agrave eacuteleveacutees Non acceacuteleacutereacutee

SFR-IDF 05 avril 2012

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 9: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

0

05

1

15

2

25

3

35

4

45

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Seacuterie1

Seacuterie2

TSH T4L

Ngdl

06 07 08 09 2010 111

Amiodarone 800cp CRT

60mg

0

5

10

15

20

25

1 2 3 4 5 6 7 8 9 10 11 12

Volume ml HII Type 2

Homme 68 ans

astheacutenie

-5 k

Toux ( asbestose)

SFR-IDF 05 avril 2012

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 10: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Preservation of Echogenicity in Type II Amiodarone-Induced Thyrotoxicosis Possible Histopathological Basis Wai Yin Wong JCEM 2010 95(11)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 11: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 12: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Amiodarone

Traitement classique

laquo choc agrave lrsquoiode raquo

SFR-IDF 05 avril 2012

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 13: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Isabelle S 55 ans

Traiteacutee par 18 cp de Cordarone (en 36 heures) Puis 120 mg propranolol

Dosage TSH (la veille) lt005

T4L LSNx2 TRAK h 48(lt2)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 14: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 15: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Nombre 21 Type Traitement Euthyroiumldie

AIT1 11

10 NT-1 B Methimazole40

+- Perchlorate

1011

(1DC preacutecoce)

AIT2 10 6 Volume N

3 goitres

1 GMHN

Prednisone 4O 1010

Etude reacutetrospective sur AIT 21 patients ( 1110) 19992006 Mono-opeacuterateur En aveugle

Publications

Color-flow Doppler Sonographyin the Diffeacuterential Diagnosis and Management of Amiodarone-Induced Thyrotoxicosis LOW M ampal Acta Radiologica 2007 (6)

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 16: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 17: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 18: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Scintigraphies

Quel traceur

99m Technecium

123 Iode Meacutemoire DIU Thyroiumldologie 2012 Ameacutelie RYNDAK

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 19: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

Clin Nucl Med 1988 Apr13(4)258-9

Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism Ling MC Dake MD Okerlund MD

SFR-IDF 05 avril 2012

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 20: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Scintigraphies

Quel traceur

99m Technecium

123 Iode

67 Gallium

99mTc-Mibi

SFR-IDF 05 avril 2012

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 21: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Publications (2) Glucocorticoid response in AIT-T2 is predicted by

thyroid Volume and serum free thyroid hormone concentration

Bogazzi F amp al JCEM 2007-92

Amiodarone induced thyrotoxicosis A review Piga M Minerva endocrinologica 2008-33 Amiodarone-induced thyrotoxicosis something new to

refine the initial diagnosis Tanda ML Eur J Endocrinol 2008-159 The usefulness of 99mTc-sestaMIBI thyroid scan in the

differencial diagnosis and management of amiodaroronee induce thyrotoxicosis

Piga M Eur J Endocrinol 2008-159

SFR-IDF 05 avril 2012

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 22: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Hyper Type 1 Hyper Type2 Hyper Type 3

Freacutequence Baisse Hausse

Meacutecanismes I- laquo carburant raquo Iodo-toxique Mixte

Thyropathie GoitreTAI autonome

non oui

Anticorps +- non +-

Terrain Homme- Carence iodeacutee

Fixation I123 Variable-preacutesente ~ 0 variable

Traitements meacutedicaux

ATS +- Cl04K Corticoiumldes(ou rien) Corticoiumldes + ATS

Echo mode B Selon thyropathie Hypoeacutechogegravene homogegravene

variable

Echodoppler Pattern + agrave +++ avasculaire variable

Doppler pulseacute LSN agrave eacuteleveacutees Non acceacuteleacutereacutee variable

Sesta MIBI Fixation MIBI Fixation = 0 +- gt inteacuterecirct Dc ++

SFR-IDF 05 avril 2012

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 23: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Autres critegraveres Elizabeth N Pearce Fausto Bogazzi Enio Martino Sandra BrogioniEnia

Pardini Giovanni PellegriniArthur B Parkes John H Lazarus Aldo Pinchera and Lewis E Braverman

The Prevalence of Elevated Serum C-Reactive Protein Levels in Inflammatory and Non inflammatoryThyroid Disease

Thyroid Volume 13 Number 7 2003

Bartalena LGrasso L Aghini-Lombardi FBraverman L EMartino E

Serum interleukin-6 in amiodarone-induced thyrotoxicosis

J Clin Endocrinol Metab 1994 78(2)

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 24: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodarone induced thyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

SFR-IDF 05 avril 2012

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 25: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

Comparaison ETAATA Bartalena L Wiersinga WM Tanda ML Bogazzi F Piantanida ELai A amp Martino E

Diagnosis and management of amiodaroneinducedthyrotoxicosis in Europe results of an international survey among members of the European Thyroid Association

Clinical Endocrinology 2004 61 494ndash502

Diehl LA Romaldini JH Graf H Bartalena L Martino E Albino CCamp Wiersinga WM Management of amiodarone-induced thyrotoxicosis in Latin America an electronic survey

Clinical Endocrinology 2006 65 433ndash438

Tanda ML Piantanida E Lai A Liparulo G Sassi L Bogazzi FWiersinga WM Braverman LE Martino E amp Bartalena L360 M L Tanda and others Diagnosis and management of amiodarone-induced thyrotoxicosis similarities and differences between North Americans and European thyroidologists

Clinical Endocrinology 2008 159

laquo hellipCFDS was the procedure of choice in both regionhellip raquo

SFR-IDF 05 avril 2012

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 26: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

SFR-IDF 05 avril 2012

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012

Page 27: Écho-Doppler thyroïdien : impact sur la prise en charge ... · PDF fileEcho mode B Selon thyropathie Echodoppler Pattern + à +++ Doppler pulsé VS LSN à élevées SFR-IDF 05 avril

laquo Take home messages raquo

LrsquoEchoDoppler thyroiumldien peut donner des arguments deacutecisifs dans lrsquooption theacuterapeutique drsquoune HII

Les endocrinologues et les cardiologues doivent le demander agrave leurs imageurs

Les imageurs doivent connaicirctre cette proceacutedure pour rendre un examen contributif

SFR-IDF 05 avril 2012